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Framework Ventures

DeFiAIGamingInfrastructure

Fund snapshot

Lookout tier
Tier 1
Lookout score
90/100
AUM
$1.4B
Vintage
2019
Check size
$250K – $40M
Stage
Seed, Series A, Series B
Role
Leads rounds

Lookout's read

How Lookout reads this fund.

Framework essentially invented the DeFi-native VC playbook — early concentrated positions in Chainlink, Aave and Synthetix gave it generational returns. It has credibly extended that into AI (co-leading Sentient). Tier 1 with a sharp identity; the flip side of concentration is cyclicality tied to the DeFi/gaming narrative.

Fund thesis

What they back.

High-conviction 'network capital': concentrate in a small number of category-defining crypto networks (DeFi, now AI and gaming) and actively participate in their tokenized economies.

Portfolio

Notable bets · 5

4 with realized tokens or exits

Chainlink

2019
OracleTokenToken live

Aave

2020
DeFiTokenToken live

Sentient

2024
AISeedActive

Illuvium

2021
GamingSeedToken live

The Graph

2020
InfrastructureTokenToken live

In their orbit

Deals Lookout covers.

Team

Who runs the capital.

Vance Spencer

@pythianism

Co-Founder & GP

Ex-Netflix; built and sold an NFL collectibles startup before going all-in on DeFi.

Michael Anderson

@im_manderson

Co-Founder & GP

Former PM at Snapchat and Dropbox; co-founded Framework in 2019.

Co-investors

Who they ride with.

Facts public-source · tier & read are Lookout judgment · profile updates continuously